trinucleotide repeat

trinucleotide repeat
Tandem repeats of three nucleotides that are present in many genes. Commonly trinucleotide repeats have undergone variable expansion in copy number, forming the basis of microsatellite markers, and occasionally resulting in the formation of alleles giving rise to genetic disease.

Glossary of Biotechnology for Food and Agriculture . 2015.

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  • trinucleotide repeat — Repetitive part of a genome that may form part of the coding sequence of a gene. The length of such repeats is frequently polymorphic, and unstably amplified repeats appear to be the major cause of such genetic diseases as Huntington s chorea,… …   Dictionary of molecular biology

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