- recombinase
- A class of enzymes that are able to alter the arrangement of DNA sequences in a site-specific way.
Glossary of Biotechnology for Food and Agriculture . 2015.
recombinase
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Recombinase — Recombinases are genetic recombination enzymes. [MeshName|Recombinases] Types include:* Cre recombinase * Hin recombinase * RecA/RAD51 * Tre recombinase * FLP recombinase … Wikipedia
Recombinase-mediated cassette exchange — In the field of reverse genetics RMCE (recombinase mediated cassette exchange) is of increasing relevance. The procedure permits the systematic, repeated modification of higher eukaryotic genomes by targeted integration. For RMCE, this is… … Wikipedia
recombinase — Enzymes that mediate site specific recombination in prokaryotes. They fall into two families, phage integrases and resolvases … Dictionary of molecular biology
recombinase — re·com·bi·nase (rē kŏmʹbə nās , nāz ) n. An enzyme that catalyzes the exchange of short pieces of DNA between two long DNA strands, particularly the exchange of homologous regions between the paired maternal and paternal chromosomes. * * * … Universalium
recombinase — noun Any of several enzymes that mediate recombination of DNA fragments between maternal and paternal chromosomes in prokaryotes … Wiktionary
recombinase — … Useful english dictionary
Site-specific recombinase technology — Site specific recombinase (SSR) technology allows for the manipulation of genetic material in order to explore gene function. The success of the Human Genome Project has made recombinant DNA technology an inevitable next step in molecular biology … Wikipedia
Cre recombinase — Cre recombinase, often abbreviated to Cre, is a Type I topoisomerase from P1 bacteriophage that catalyzes site specific recombination of DNA between loxP sites. The enzyme does not require any energy cofactors and Cre mediated recombination… … Wikipedia
Tre recombinase — is an experimental enzyme that in lab tests has successfully removed DNA inserted by HIV from infected cells [Sarkar, I. et al. (2007): HIV 1 proviral DNA excision using an evolved recombinase. In: Science. Bd. 316, S. 1912 1915. PMID 17600219… … Wikipedia
Hin recombinase — is a 21kD protein composed of 198 amino acids that is found in the bacteria Salmonella. Hin belongs to the serine recombinase family of DNA invertases in which it relies on the active site serine to initiate DNA cleavage and recombination. The… … Wikipedia
