nucleic acid probe
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Nucleic acid design — can be used to create nucleic acid complexes with complicated secondary structures such as this four arm junction. These four strands associate into this structure because it maximizes the number of correct base pairs, with A s matched to T s and … Wikipedia
Nucleic acid thermodynamics — is the study of the thermodynamics of nucleic acid molecules, or how temperature affects nucleic acid structure. For multiple copies of DNA molecules, the melting temperature (Tm) is defined as the temperature at which half of the DNA strands are … Wikipedia
Nucleic acid structure determination — This article is about the experimental determination of nucleic acid structure. For computational methods, see Nucleic acid structure prediction. Structure probing of nucleic acids is the process by which biochemical techniques are used to… … Wikipedia
Nucleic acid hybridization — Hybridization is the process, discovered by Alexander Rich, of combining complementary, single stranded nucleic acids into a single molecule. Nucleotides will bind to their complement under normal conditions, so two perfectly complementary… … Wikipedia
nucleic acid test — any of various tests that use molecular biology techniques to detect and identify microorganisms, including viruses, on the basis of their nucleic acids. It includes culture confirmation tests, which identify organisms grown in culture, and… … Medical dictionary
Locked nucleic acid — A locked nucleic acid (LNA), often referred to as inaccessible RNA, is a modified RNA nucleotide. The ribose moiety of an LNA nucleotide is modified with an extra bridge connecting the 2 and 4 carbons. The bridge locks the ribose in the 3 endo… … Wikipedia
Probe — (1) In surgery, a probe is a slender flexible rod with a blunt end used to explore, for example, an opening to see where it goes. (2) In molecular genetics, a probe is a labeled bit of DNA or RNA used to find its complementary sequence or locate… … Medical dictionary
probe — (prōb) A short, labeled nucleic acid segment complementary in base sequence to part of another nucleic acid, which is used to identify or isolate the particular nucleic acid from a mixture through its ability to bind specifically with the target… … Dictionary of microbiology
probe — n. 1) a thin rod of pliable metal, such as silver, with a blunt swollen end. The instrument is used for exploring cavities, wounds, fistulae, and sinus channels. 2) (dental probe) a hand instrument designed for specific exploratory examination… … The new mediacal dictionary
probe — A labelled DNA or RNA sequence used to detect the presence of a complementary sequence by hybridization with a nucleic acid sample … Glossary of Biotechnology
