- allelic exclusion
- A phenomenon whereby only one functional allele of an antibody gene can be assembled in a given B lymphocyte.
Glossary of Biotechnology for Food and Agriculture . 2015.
allelic exclusion
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Allelic exclusion — Humans and many other organisms are diploid , i.e. they have two copies of each chromosome (one inherited from each parent) in all their somatic cells. Both chromosomes within the pair contain essentially the same genes, but these genes may… … Wikipedia
allelic exclusion — The process whereby one or more loci on one of the chromosome sets in a diploid cell is inactivated (or destroyed) so that the locus or loci is (are) not expressed in that cell or a clone founded by it. For example in mammals one of the X… … Dictionary of molecular biology
allelic exclusion — a mechanism that allows the expression of only one of a set of alleles, such as the expression of a single immunoglobulin by any one B lymphocyte or plasma cell or the expression of a single T cell receptor by any one T lymphocyte … Medical dictionary
exclusion — A shutting out; disconnection from the main portion. [L. ex cludo, pp. clusus, to shut out] allelic e. in each cell of an individual heterozygous at an autosomal locus, the non preferential suppression of the phenotypic manifestation of one or… … Medical dictionary
Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… … Wikipedia
Аллельное исключение — Аллельное исключение процесс, при котором в диплоидной клетке экспрессируется лишь один аллель гена, в то время как экспрессия другого аллеля подавлена. Существует два разных механизма аллельного исключения. В первом случае аллель гена… … Википедия
Anticuerpo — Molécula de inmunoglobulina con su típica forma de Y. En azul se observan las cadenas pesadas con cuatro dominios Ig, mientras que en verde se muestran las … Wikipedia Español
Adaptive immune system — The adaptive immune system is composed of highly specialized, systemic cells and processes that eliminate or prevent pathogenic challenges. Thought to have arisen in the first jawed vertebrates, the adaptive or specific immune system is activated … Wikipedia
Antonio Lanzavecchia — (born October 9, 1951) is an Italian immunologist. He was born in Varese, Italy. In 1976 he obtained his degree with honors in Medicine at the University of Pavia where he specialized in Pediatrics and Infectious Diseases. From 1983 to 1999 he… … Wikipedia
IGLL1 — Immunoglobulin lambda like polypeptide 1, also known as IGLL1, is a human gene.cite web | title = Entrez Gene: IGLL1 immunoglobulin lambda like polypeptide 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… … Wikipedia
