T4 DNA ligase

T4 DNA ligase
An enzyme, present in bacteria infected with bacteriophage T4, which catalyses the joining (ligation) of, and repairs nicks in, duplex DNA molecules. Ligation activity requires that one DNA molecule has a 5'-phosphate group, and that the other has a free 3'-hydroxyl group.

Glossary of Biotechnology for Food and Agriculture . 2015.

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  • DNA ligase — DNA li·gase (liґgās) an enzyme of the ligase class that catalyzes the energy driven linkage of a double stranded DNA chain with a free 3′ hydroxyl group to one with a 5′ phosphate group, forming a phosphodiester bond between them …   Medical dictionary

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  • DNA ligase —    An enzyme that catalyzes nucleotide phisphodiester bond formation …   Forensic science glossary

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