somatic hypermutation

somatic hypermutation
The high frequency of mutation that occurs in the gene segments encoding the variable regions of immunoglobulins during the differentiation of B lymphocytes into antibody producing plasma cells.

Glossary of Biotechnology for Food and Agriculture . 2015.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Somatic hypermutation — (or SHM) is a mechanism inside cells that is part of the way the immune system adapts to the new foreign elements which confront it (for example, microbes). SHM diversifies the receptors that the immune system uses to recognize foreign elements… …   Wikipedia

  • somatic hypermutation — extremely high frequency point mutations that occur in the genes coding immunoglobulin heavy and light chain V regions during B lymphocyte maturation, leading to the increased affinity of antibodies for antigen seen in the secondary immune… …   Medical dictionary

  • Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… …   Wikipedia

  • Hipermutación somática — La hipermutación somática (o SHM, por sus siglas en inglés) es un mecanismo celular, que forma parte del modo en cómo se adapta el sistema inmune a nuevos elementos extraños (por ejemplo bacterias). Su función es diversificar los receptores que… …   Wikipedia Español

  • AICDA — Activation induced cytidine deaminase, also known as AICDA, is a human gene.cite web | title = Entrez Gene: AICDA activation induced cytidine deaminase| url = Cmd=ShowDetailView TermToSearch=57379| …   Wikipedia

  • Anticuerpo — Molécula de inmunoglobulina con su típica forma de Y. En azul se observan las cadenas pesadas con cuatro dominios Ig, mientras que en verde se muestran las …   Wikipedia Español

  • Systemic lupus erythematosus — For other uses, see lupus (disambiguation). Systemic lupus erythematosus Classification and external resources The typical butterfly rash found in lupus ICD 10 L …   Wikipedia

  • Adaptive immune system — The adaptive immune system is composed of highly specialized, systemic cells and processes that eliminate or prevent pathogenic challenges. Thought to have arisen in the first jawed vertebrates, the adaptive or specific immune system is activated …   Wikipedia

  • Hipermutación — Saltar a navegación, búsqueda Hypermutation somáticas (o SHM) es un mecanismo dentro de las células que es parte de la forma en que el sistema inmune se adapta a los nuevos elementos extranjeros que se enfrentan (por ejemplo, microbios). SHM… …   Wikipedia Español

  • Hypergammaglobulinemia — Infobox Disease Name = PAGENAME Caption = DiseasesDB = ICD10 = ICD10|D|89|0|d|80, ICD10|D|89|2|d|80 ICD9 = ICD9|289.89 ICDO = OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = D006942 Hypergammaglobulinemia is a medical condition… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”