- homogenotization
- An allele replacement technique, in which a bacterial cell is transformed with a plasmid containing an altered copy of the target sequence, and a double recombination event effects the substitution of the wild type allele by the altered one. An antibiotic resistance gene is usually fused to the altered copy in the plasmid, so that double recombinants can be selected.
Glossary of Biotechnology for Food and Agriculture . 2015.