germ cell gene therapy

germ cell gene therapy
The repair or replacement of a defective gene within the gamete-forming tissues, resulting in a heritable change in an organism's genetic constitution.

Glossary of Biotechnology for Food and Agriculture . 2015.

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  • germ line gene therapy — The delivery of a gene or genes to a fertilized egg or an early embryonic cell. The transferred gene(s) is present in all or some of the nuclei of the cells of the mature individual, including possibly the reproductive cells, and alters the… …   Glossary of Biotechnology

  • Gene therapy — using an Adenovirus vector. A new gene is inserted into an adenovirull. If the treatment is successful, the new gene will make a functional protein. Gene therapy is the insertion, alteration, or removal of genes within an individual s cells and… …   Wikipedia

  • gene therapy — n the insertion of usu. genetically altered genes into cells esp. to replace defective genes in the treatment of genetic disorders or to provide a specialized disease fighting function (as the destruction of tumor cells) gene therapist n * * *… …   Medical dictionary

  • gene therapy — treatment directed to curing genetic disease by introducing normal genes into patients to overcome the effects of defective genes, using techniques of genetic engineering. The most radical approach would be to do this at a very early stage in the …   The new mediacal dictionary

  • gene therapy — The proposed treatment of an inherited disease by the transformation of an affected individual with a wild type copy of the defective gene causing the disorder. In germ line (or heritable) gene therapy, reproductive cells are transformed; in… …   Glossary of Biotechnology

  • Gene — For a non technical introduction to the topic, see Introduction to genetics. For other uses, see Gene (disambiguation). This stylistic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). The… …   Wikipedia

  • Gene knockout — A gene knockout (abbreviation: KO) is a genetic technique in which one of an organism s genes is made inoperative ( knocked out of the organism). Also known as knockout organisms or simply knockouts, they are used in learning about a gene that… …   Wikipedia

  • Germ line — 1. The sequence of cells which develop into eggs and sperm. 2. Inherited material that comes from the eggs or sperm and is passed on to offspring. * * * germ line n the cellular lineage esp. of a sexually reproducing animal from which eggs and… …   Medical dictionary

  • therapy — 1. The treatment of disease or disorder by any method. SEE ALSO: therapeutics. 2. In psychiatry, and clinical psychology, a short term for psychotherapy. SEE ALSO: psychotherapy …   Medical dictionary

  • Stem cell — Mouse embryonic st …   Wikipedia

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