major histocompatibility antigen

major histocompatibility antigen
A cell-surface protein or glycoprotein that allows the immune system to distinguish foreign or "non-self" from "self". A better term is histoglobulin. These are the antigens that must be matched between donors and recipients during organ and tissue transplants to prevent rejection.

Glossary of Biotechnology for Food and Agriculture . 2015.

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  • Major histocompatibility complex — The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates that encodes MHC molecules. MHC molecules play an important role in the immune system and autoimmunity. Proteins are continually… …   Wikipedia

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  • histocompatibility antigen — noun : any of the antigenic glycoproteins on the surface membranes of cells that enable the body s immune system to recognize a cell as native or foreign and that are determined by the major histocompatibility complex * * * Immunol. any antigen… …   Useful english dictionary

  • Minor histocompatibility antigen — are receptors on the cell surface of donated organs that are known to give an immunological response in some organ transplants[1]. They cause problems of rejection less frequently than those of the major histocompatibility complex (MHC). Minor… …   Wikipedia

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